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Author contributions: M. Water channel aquaporin 4 AQP4 plays a key role in the regulation of water homeostasis in the brain. It is predominantly expressed in astrocytes at the blood—brain and blood—liquor interfaces. Although several AQP4 isoforms have been identified in the mammalian brain, two, AQP4a M1 and AQP4c M23 , have been confirmed to cluster into plasma membrane supramolecular structures, termed orthogonal arrays of particles OAPs and to enhance water transport through the plasma membrane. However, the role of the newly described water-conductive mammalian isoform AQP4e is unknown. Here, the dynamics of AQP4e aggregation into OAPs and its role in the regulation of astrocyte water homeostasis have been studied. Using super-resolution structured illumination, atomic force, and confocal microscopies, the results revealed that, in female rat astrocytes, AQP4e isoform colocalizes with OAPs, affecting its structural dynamics.

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The data records will follow and are the same as they have been all along, with the exception that tas is no longer encoded. Additional meta-data may present. The PMS-2D raw data comes in 4 kilo-byte records of 32 bit slices from the probe slices. The interface card then wraps a record header around that with time stamp and other pertinent information. The Fast2D raw data comes in 4 kilo-byte records of 64 bit slices from the probe slices. The data is stored in big-endian format, so all data will need to be swapped when used on Intel architecture Linux or MS Windows.

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Are your over 50, single and gay? Gay senior dating has its own challenges, but online websites are fast changing the face of dating today. SilverSingles, one of the leading senior gay dating sites, is created for senior singles to connect and discover companionship, love and relationships. So how does it work? Getting back into dating and meeting a compatible partner can sometimes feel like a difficult undertaking.

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Some can be used as ice breakers, some good for students, but above all, all give you a great list of things to say. Find a speed dating event near you. There are plenty of great useful speed dating questions there; just pick and choose a few for your evening. Speed Dating Questions. Where are you from originally? Are you more of a city or country person? How would your best friend describe you? What is your dream job?

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About The Journal. All submissions can be done at our Online Manuscript Submission System. Authors are requested to submit their articles directly to Online Manuscript Submission. Cell, Cell biology, Cell human genetics, Cell replacement therapy, Cell signalling, Cell systems biology, Cell therapeutics, Cell therapy bioprocessing, Cell therapy products, etc. Remaining Scope can be viewed at Aim and Scope. Manuscript template: Title, List of authors, their affiliations and email addresses, Abstract, Introduction, Main body, Results and discussion, Conclusions, Acknowledgments optional , References.

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Remaining Scope can be viewed at Aim and Scope. Manuscript template: Title, List of authors, their affiliations and email addresses, Abstract, Introduction, Main body, Results and discussion, Conclusions, Acknowledgments optional , References.

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AQP4e-Based Orthogonal Arrays Regulate Rapid Cell Volume Changes in Astrocytes

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Strapp, J. Albers, A. Reuter, A. Korolev, U. Maixner, E. Rashke, and Z. Oceanic Technol. Laboratory measurements of the response of the Particle Measuring Systems, Inc. Response times also varied significantly, from 0. Measurements of the depth of field for known particle sizes at low velocity agreed well with published calculations at zero velocity. The average particle size also decreased with increasing airspeed but did so in such a manner as to counteract oversizing due to out-of-focus images.

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There’s a reason why post-retirement age could be the happiest time of your life. Golden years, hello? Yes, there may be fewer potential partners in the dating pool, but if you think about it, that just makes everything less overwhelming. Use this guide to figure it out. Let’s start by saying that it’s totally normal to feel hesitant about making the jump to online dating.

That age group does have a few more options, which may be another reason that you’re feeling iffy about online dating if you’re a baby boomer. However, youth has a disadvantage you may not have considered: Many people in their 20s and 30s just aren’t ready to settle down yet. Developing a crush on someone is more likely to end up in an awkward “situation-ship” rather than a serious relationship and we all know how fun that is.

Dating over 60 means you’re at an age when you know what you want and you’re not afraid to put it all out there.

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